Accutane (isotretinoin) can be prescribed by your health care provider for the treatment of severe nodular acne. It's therefore very important that you present proof you already tried taking other drugs but they did not work for your acne. This medicine can make your skin more sensitive to sunlight. Make sure you wear protective clothes if you have to stay outside for a long time. Accutane is FDA pregnancy category X - it will harm an unborn child if taken by a pregnant woman in spite of the trimester. Stop taking Accutane if you think you may have become pregnant and contact your doctor. At least two forms of birth control must be used while Accutane id taken to prevent a pregnancy. Both mild and serious side effects are possible when Accutane is taken. You may need to talk to your doctor if your mild side effects change in intensity or get bothersome, especially the following ones that are not expected to last for too long: changes in skin color, sweating, slowed healing of cuts, tiredness, hair loss, changes in the nails, dry skin, nosebleeds, voice changes, cold symptoms, dry mouth, sore lips, and flushing, although other side effects are also possible and should be considered individually.